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Centre of Sustainable Chemistry

Reaction and Process Design

  • COILSIM1D: simulation and optimization software for steam cracking processes
  • GCxGC analysis equipment for complex mixtures of feed/reaction products
  • Bench scale units for kinetic experiments
  • Temporal Analysis of Products (TAP) for puls-respons experiments
  • Two high-throughput kinetics set-ups for catalyst testing
  • Pyrolysis reactors for the thermochemical conversion of biomass
  • Microreactor equipment
  • CFD simulation tools
  • Tools for exergetic sustainability and life-cycle assessments

Industrial Biotech

  • Enzyme engineering: specialized software for protein modeling and docking (Yasara Structure)
  • Automated screening platform: high-throughput robots for colony picking and for liquid handling; microplate reader
  • Microbiology/molecular biology: PCR; electrophoresis; electroporation; laminar flow; bioreactors with shaking, T-control and data acquisition software; Bioscope Plug-flow reactor for rapid sampling experiments; Metabolic Flux Analysis Software (MFA); software for DNA and RNA analysis; …
  • Purification/DSP (downstream processing): evaporators; (continuous) centrifuges; lyophilisator; …
  • Product analysis: GC/HPLC with UV-VIS, IR, PAD, ELSD and MS detection
  • Microbial electrochemistry: rotating disc electrode for probing kinetics of anaerobic microbial metabolism; membrane electrolysis materials such as a potensiostat, custom-made Perspex plate-and-frame reactor, ion exchange membranes, iridium oxide coated titanium anodes, variety of cathode materials

Advanced Materials

  • Molecular characterization: structure elucidation with NMR, MALDI-TOF, on-line IR, GC- and LC-MS analysis, chiral HPLC, …
  • Structural characterization: determination of molecular weight and molecular weight distribution of polymers via SEC and 2D LC/SEC; microstructural and crystallographical analysis of powders and thin layers; texture analysis; …
  • Behaviour of solutions via turbidimetry, light scattering, determination of particle size, viscosimetry, …
  • Surface visualization and characterization: measurement of microscopic features and microstructures at nanoscale supported by optical microscopy, SEM, TEM, AFM, IR mapping, XRD, XPS; surface interaction via static and dynamic contact angle measurements; quartz crystal microbalance-coupled ellipsometry
  • Thermal and mechanical analysis: study of thermal behaviour via differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA); study of mechanical behaviour via dynamic mechanical analysis (DMA), rheology and materials testing equipment

The Pilot Steam Cracker

LCT disposes of a pilot plant unit for the thermal cracking of hydrocarbons, next to a number of bench-scale units. These experimental set-ups are used to determine the kinetics of the cracking reactions and of coke deposition in both the radiant coil and the transfer line exchanger (TLE). Fouling inhibition in reactor and TLE is also studied. Major advantage of the pilot unit is its extremely flexibility. A wide variety of hydrocarbons, ranging from gaseous feeds to waxes, can be handled. Moreover, the reactor design allows to obtain a broad range of process conditions. The pilot plant also offers the opportunity to industrial groups to test industrially important and/or new feeds, additives, coatings etc. in pilot plant experiments done by LCT personnel.

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    Material characterization

    COURSE OVERVIEW

    This course gives an introduction on the (pharmaceutical) relevance of (raw) material characterization. An overview is given about the relevant characterization methods on the market, their applicability and how the material properties can be used to describe the processability.
    This 1-day course consists out of a theoretical (interactive) and hands-on part.


    MODULE 1: BASIC COURSE

    Theoretical

    The trainee will get an in-depth explanation about the different characterization methods, their (pharmaceutical) relevance and what you can do with the generated data.
    Some of the key material characteristics described are:

    Flow/cohesion
    &
    Particle size and shape
    &
    Density and porosity
    &
    Electrostatic charge
    &
    Melting point and crystal structure
    &
    Viscosity

    Practical

    Hands-on sessions will allow the trainee to get a feel with what it takes to characterize a material.
    The extensive array of characterization equipments, available at CESPE, will be made available to visualize the difference between highly divergent powders.
    Some of the equipment that will be used are:

    FT4 Powder Rheometer
    &
    Schulze Ring Shear Tester
    &
    GranutoolsTM equipment
    &
    Malvern Laser diffractors
    &
    DVS and DSC equipment

    Upon request, a powder of interest could be tested on the available equipment!
    For more information, please contact Sarah.Costers@UGent.be .


    COURSE PROGRAMME

    A detailed overview of the course can be found in the following document.


    If you are interested in taking this course, please email Mark (mark.gontsarik@ugent.be).