COURSE OVERVIEW
Twin screw granulation 101 focusses on giving a thorough introduction about the granulation process in an interactive manner (both theoretical and hands-on).
This course can be divided into three separate modules:
Module 1: Basic course: Introduction to twin screw wet granulation (1-day module)
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Module 2: Basic course: Introduction to twin screw hot-melt granulation (1/2-day module)
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Module 3: Specialized courses (1/2-day module)
MODULE 1: WET GRANULATION
Theoretical
The trainee will get an in-depth explanation about the basic twin screw wet granulation aspects such as:
Equipment overview
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Principles of wet granulation
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Batch vs continuous manufacturing
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Process and formulation parameters
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Granule characterization
Practical
The in-house ConsiGmaTM -25 line will be used to demonstrate the twin screw wet granulation process. Afterwards, the produced granules will be tested using the available granule characterization methods.
The hands-on session consists out of:
ConsiGmaTM-25 demonstration with placebo
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Introduction to granule characterization methods
MODULE 2: HOT-MELT GRANULATION
Theoretical
The trainee will get an in-depth explanation about the basic twin screw hot-melt granulation aspects such as:
Equipment overview
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Fundamentals of hot-melt granulation
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Equipment configurations and settings
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Pitfalls
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Granule characterization*
*Will be skipped if module 1 was followed as well.
Practical
The trainee will be able to follow and help during placebo trials using a twin screw hot-melt granulator. The influence of process and formulation parameters will be demonstrated.
MODULE 3: SPECIALIZED COURSES
In this module, the goal is to highlight specific aspects of the granulation process through different use-cases. Each use-case allows the trainee to get an in-depth comprehension of a specific part of the process.
Topics
Wet granulation: Modified release formulations
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Wet granulation: Impact of dry or wet addition
The trainee has the option to take up all of the provided topics, covering a half day course, or select a sub-set of these topics.
COURSE PROGRAM
A detailed overview of the different modules can be found in the following document.
If you are interested in following this course, please take a look at the planned sessions.
For further questions or requests, please use the contact form.