COURSE OVERVIEW
Lyophilization 101 focusses on giving a thorough introduction about pharmaceutical freeze-drying in an interactive manner (both theoretical and hands-on).
Throughout this 2-day course, the trainee gets to understand the basic and fundamental aspects from start untill finished product.
MODULE 1: BASIC COURSE
Theoretical – day 1
During the first day of the course, the trainee will get an in-depth explanation about the basic freeze-drying principles such as:
Freeze-drying equipment
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Heat and mass transfer mechanisms
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(Dis)advantages
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Modelling of the freeze-drying cycle
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Optimization of the process
Practical – day 1
Hands-on sessions will allow the trainee to get a feel with the freeze-drying process.
The hands-on session will cover:
Tour of the CESPE freeze-drying lab
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Sample preparation and characterization
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Starting your first run
Theoretical – day 2
During the second day, the focus will be put on PAT implementation and post-run analytics, allowing the trainee to deep-dive in the generated data.
Process analytical technologies (PAT)
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Pre- and Post-run analytics
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The future of freeze-drying: Continuous vs. Batch
Practical – day 2
Hands-on sessions during day 2 will mainly focus on the analysis of the performed run of practical day 1.
The hands-on session will cover:
Evaluation of the freeze-drying run
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Water content determination
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DSC
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Sneak-peek at a continuous freeze-dryer
COURSE PROGRAM
A detailed overview of the program can be found in the following document.
If you are interested in taking this course, please email sarah.costers@ugent.be or mgadbruy.debruyne@ugent.be.