Category: Industrial members

PROCEPT, established in 1994, specializes in small-scale particle processing equipment for R&D and GMP applications. They offer innovative solutions in drying, agglomeration, coating, and melting, catering to the pharmaceutical, biotech, fine chemicals, nutraceuticals, and food industries. PROCEPT collaborates with its sister company XEDEV, providing comprehensive formulation, process development, and scale-up services. Known for their expertise in spray drying, PROCEPT emphasizes strong engineering and advanced technology to ensure efficient and effective particle engineering processes.

OTHER INDUSTRIAL MEMBERS

GEA, founded in 1881, is one of the world’s largest systems suppliers for the food, beverage and pharmaceutical sectors with more than 18.000 employees. Their portfolio includes machinery and plants as well as advanced process technology. Some of their core technologies within the pharma & healthcare department include continuous unit operations such as feeding, continuous blending, twin screw granulation and tableting. The company has pioneered continuous manufacturing in drug production and was the first supplier to provide and install a complete powder-to-tablet line.

GEA’s pharmaceutical technology test centers in Belgium, Denmark, Germany, the UK, the USA, Singapore, China and South Korea provide global technical support and know-how to the pharmaceutical industry.

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UCB’s ambition is to transform the lives of people living with severe diseases, allowing them to live the best life that they can – as free as possible from the challenges and uncertainty of disease. That commitment comes to life in our research and development activities across neurology, immunology and other areas where our expertise, innovation and ambition align with unmet needs.

UCB is continuously working to advance science and embrace new knowledge, bringing passion and leadership to solving the challenges that matter to people living with severe diseases. We are leveraging scientific advances and new technologies in areas including genetics, biomarkers and human biology. Continually inspired by those we serve to bring differentiated solutions with unique outcomes that deliver tangible, positive impacts.

With more than 8700 employees in approximately 40 countries, they are a global biopharmaceutical company headquartered in Brussels, Belgium which invests more than 25% of revenue in cutting-edge scientific research to meet unmet patient needs.

OTHER INDUSTRIAL MEMBERS

Antibody drugs are now widely accepted in companion animal health. 272BIO is developing a pipeline of VHH based therapeutic and prophylactic drug to address complex diseases at affordable prices for both developers and customers. The flexibility and modularity of VHH, combined with their suitability to be produced across many different microbial expression systems make them highly suitable for the development of bi- and multi-valent drugs targeting different pathophysiological pathways. 

272BIO is making use of the advantages of VHH to develop innovative second-generation treatments for complex diseases including canine atopic dermatitis, osteoarthritis, oncology etc.

A key goal for 272BIO is to develop VHH antibody drugs to transform the lives of patients by addressing the different drivers of disease to result in superior clinical efficacy and better disease control.  Development costs, modest market sizes and high drug prices represent barriers to entry for animal health companies, prescribers and pet-parents as well. To overcome these hurdles necessitates the use of expression and manufacturing processes suitable for the challenges of animal health

The experienced team of seasoned antibody scientists can also assist start up biotech and animal health companies in designing and driving their discovery and development phases for their products.

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AM-Team was founded in 2017 by Dr. Wim Audenaert, Dr. Usman Rehman, and Prof. Ingmar Nopens, all having MSc and PhD degrees in either chemical or environmental engineering. AM-Team is a spinoff company of Ghent University with over a decade of expertise in process modelling and simulations.

Customers from all over the globe rely on their leading-edge simulation services and digital tools. They keep on developing tailored digital solutions to match the needs of their customers in the process industry.

They do this by: 

• Developing new process models and methodologies to maximise customer experience and cater the industry needs
• Sharing their expertise at high-level international events and publishing new findings in peer-reviewed scientific papers, often together with customers
• Investing in new hardware and software to maximise simulation speed and accuracy

Thanks to their large team of dedicated simulation engineers, they can handle large projects in a short timeframe. 

OTHER INDUSTRIAL MEMBERS

Through our divisions BioSPX (Life Sciences), ChemSPX (Organic Chemistry and Chromatography) and SciSPX (Sample Prep and Analysis) we help laboratories with their research and analysis.

As experts in our fields we focus on establishing long-term relationship with our customers and partners.

We make your innovation our goal!

• BRS stands for the exclusive distribution of high-end laboratory solutions in Belgium and Luxemburg.
• We introduce new technologies and innovations of existing systems.
• We guarantee an optimal and continued operation of your laboratory at all times.
• You can count on an optimal technical support by our service & support team.
• BRS is committed to providing the highest level of sales, service & support to our customers.
• At BRS the customer comes first.
• Working together as a team and in close cooperation with our customers is the key.
• We believe in an open communication.
• The BRS team focuses on YOUR results.

OTHER INDUSTRIAL MEMBERS

Every decision we take at Comate, is to make a hardware solution more successful. Our team of 90+ engineers and designers, will give a high-tech hardware idea the biggest chance on success. From tracking and monitoring solutions over precision mechanics to high end machinery and automation innovations. We focus on wide technical expertise in combination with user experience and designs that will reflect the quality of the product. Our success is measured by the quality of the products we deliver.

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Elegent, a UGent spin-off company, is a dynamic modelling consultancy firm, dedicated to optimizing pharmaceutical development processes. Within the CESPE consortium, we bring invaluable expertise in data-driven and physics-based pharmaceutical engineering. Their focus is accelerating drug product production of solid oral dosages via continuous direct compression and wet granulation through advanced modelling techniques. With a commitment to sustainability and innovation, Elegent complements the consortium’s mission to revolutionize pharmaceutical manufacturing.

The expertise at Elegent centres on bridging the gap between academic innovations and practical applications in pharmaceutical engineering. Within the CESPE consortium, their specialization is utilizing quantitative data-driven support for drug product development. They excel in custom process modelling, formulation, process development, and process analytical technology (PAT) implementation. By leveraging their extensive knowledge in pharmaceutical technology and data science, they help CESPE and its industrial partners drive sustainable innovation, enabling efficient pharmaceutical care delivery to patients.

OTHER INDUSTRIAL MEMBERS

Fette Compacting is a world-leading supplier of high-tech process equipment for the pharmaceutical industry.

Headquartered near Hamburg, with Sales & Service offices in all major markets, Fette Compacting designs, builds, sells and services worldwide sophisticated machines for the production of pharmaceutical tablets and capsules. The combination of high speed, high precision and full automation requires the very best engineering skills in the fields of mechanical, electronics, software and process design.

Fette Compacting Belgium, located in Mechelen, is the group’s innovation centre for the development and launch of new technologies and machines for faster and more precise pharmaceutical production.

OTHER INDUSTRIAL MEMBERS

At Pfizer, they apply science and their global resources to bring therapies to people that extend and significantly improve their lives. They strive to set the standard for quality, safety, and value in the discovery, development, and manufacture of health care products.

Their global portfolio includes medicines and vaccines as well as many of the world’s best-known consumer health care products. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments, and cures that challenge the most feared diseases of our time.

Consistent with their responsibility as one of the world’s premier innovative biopharmaceutical companies, they collaborate with health care providers, governments, and local communities to support and expand access to reliable, affordable health care around the world.

Their R&D Priorities and Strategy

• Delivering a pipeline of highly differentiated medicines and vaccines where they have a unique opportunity to bring the most important new therapies to patients in need
• Advancing their capabilities that can position them for long-term R&D leadership
• Advancing new models for partnerships with creativity, flexibility and urgency to deliver innovation to patients as quickly as possible.

Pfizer Manufacturing Belgium, the largest production and packaging site of Pfizer worldwide, has now joined the CESPE Innovation cluster. The site has an extensive manufacturing setup with a range of formulation booths, filling lines, automatic inspection lines, packaging lines, freeze driers, and lab facilities. With their clinical pilot plant and experimental plant Pfizer Puurs is also known as a Launch Site within the Global Pfizer network, providing them the ability to quickly scale-up to commercial manufacturing of a new product.

OTHER INDUSTRIAL MEMBERS

RheaVita sells single vial (for R&D), non-GMP multi-vial (for scale-up and stability studies), and full GMP continuous freeze-drying systems.

Next to our engineered solutions we also offer freeze-drying related CDMO services. The freeze-drying of biopharmaceuticals, LNP-based formulations, ATMPs, and other small and large molecules, requires proper formulation and process optimization of the drug substance. Designing the optimal formulation based on the drug substance properties and characteristics is crucial. Furthermore, by applying a model-based strategy, RheaVita provides the opportunity to efficiently design and optimize your freeze-drying process in an extremely fast way with limited product consumption. 

Our manufacturing approach avoids scale-up issues, reduces cycle times, allows fast product development, reduces time-to-patient, lowers production costs, makes use of smaller manufacturing installations, requires less clean room space, provides improved quality assurance thanks to PAT (100% inspection with inherent potential for real-time-release) and leads to improved and uniform product quality and process uniformity.

RheaVita has also set up an academy to share knowledge on freeze-drying where our customers receive a fundamental insight into freeze-drying and analysis of the results and experience the benefits of continuous manufacturing technology.

OTHER INDUSTRIAL MEMBERS

Secoya Technologies is a global provider of services and equipment in particle engineering for the (bio)-pharmaceutical industry. Secoya’s experts have been developing innovative production technologies and equipment by a smart use of micro-structured elements, enabling a faster, precise and secure development and production process.

Their ranges of robust intensified reactors guarantee a stable and reliable production process – at different scale – of high quality (bio-)pharmaceutical products. Their core principle is applied to following technologies and in-house expertise service:

• Crystallization (small molecules, API, excipients…)
• Emulsification / Encapsulation (simple and double emulsion for encapsulation of biomolecules, API…)
• Pervaporation
• Process intensification

The integration of their unique, robust and versatile technologies in their equipment, combined with their unique know-how, allows them to guide their partners with mastering every aspect of the manufacturing process, from laboratory scale to commercial production scale the size of the particles generated and their size distribution as well as to increase the efficiency, productivity and flexibility. Whether it is the development of new products or the improvement of existing products, Secoya’s technologies provide many key benefits:

• Unmatched product quality and secure production
• Implementation of Quality-by-Design
• Reduction of investment cost and risk for the process development
• Reduction of cost of goods sold
• Inherent compatibility with continuous manufacturing
• Manufacturing of new possible molecules

OTHER INDUSTRIAL MEMBERS

Takeda Pharmaceutical Company Limited is a global, values-based, R&D-driven biopharmaceutical leader headquartered in Japan, committed to discover and deliver life-transforming treatments, guided by their commitment to patients, their people and the planet.

Takeda focuses its R&D efforts on four therapeutic areas: Oncology, Rare Genetic and Hematology, Neuroscience, and Gastroenterology (GI). They also make targeted R&D investments in Plasma-Derived Therapies and Vaccines.

They are focusing on developing highly innovative medicines that contribute to making a difference in people’s lives by advancing the frontier of new treatment options and leveraging their enhanced collaborative R&D engine and capabilities to create a robust, modality-diverse pipeline.

Their employees are committed to improving quality of life for patients and to working with our partners in health care in approximately 80 countries.

OTHER INDUSTRIAL MEMBERS