CESPE unites data science, analytical technology, automation, and sustainable design to transform pharmaceutical manufacturing into a smarter, greener, and more connected enterprise. These disciplines connect researchers across fields that have numerous applications in drug substance and drug product manufacturing, enabling innovation, integration, and intelligent control at every level of the process lifecycle.
Data Science, Modelling & Control
Modelling of Manufacturing Unit Operations
Discreet Element Method (DEM) Modelling of Gravimetric Feeding
Develop a DEM model to obtain fundamental understanding of the LIW feeding system and inform design process
Computation Fluid Dynamics – Discreet Element Modelling of Coating in a Fluidized Bed Reactor
Development of a CFD-DEM model of the fluidization and the coating process to find operational boundaries and provide insights into coating kinetics.
Computation Fluid Dynamics of Spin Freezing Process
Development of a CFD model to understand the cooling gas dynamics for further optimizing the freezing process.
Mechanistic Modelling of Freeze-Drying with Microwaves
Develop a model to support the experimental campaign on microwave freeze-drying.
Process Control and Optimization
okay
Modelling of Biomanufacturing Processes
okay
Analytical Technology & Characterisation
Process Analytical Technology (PAT)
NIR
Okay
Raman
Okay
Particle Size
Okay
Infrared Camera
Okay
Raw Material & Product Characterisation
Physical Characterisation
True Density
Okay
Dissolution
Okay
Freeze-drying Microscope
Okay
Flowability
Okay
Envelope Density
Okay
Triboelectric Charging
Okay
Rheometry
Okay
Particle Size
Okay
Disintegration
Okay
Bulk/Tapped density
Okay
Friability
Okay
Tablet Hardness
Okay
DSC
Okay
Texture Analysis
Okay
DVS
Okay
Spectroscopic Characterisation
Transmission Raman
Okay
FT-NIR
Okay
FT-IR ATR
Okay
UV-VIS
Okay
NIR-CI
Okay
Assay & Analysis
UPLC
Okay
HPLC
Okay
Karl Fisher
Okay
Osmometry
Okay
Sustainable Systems, Engineering & Design
Okay
Automation
Okay